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While passengers onboard the MV Hondius say the situation is calm, they face days at sea as officials warn the disease may have spread.
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Spain said it would decide on a port of call only after disease experts inspected the vessel. The World Health Organization said human-to-human transmission may have played a role in the outbreak.
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Three passengers of the MV Hondius died after showing symptoms of the rare disease. Health authorities confirmed two cases and are investigating five others.
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The cruise ship carrying almost 150 passengers at the center of a deadly hantavirus outbreak was marooned in the Atlantic Ocean on Tuesday, waiting for two ill crew members to be evacuated for treatment.
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The World Health Organization said the risk to the wider public was low but added that limited human-to-human transmission had been reported in some strains of the virus.
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Medical personnel will focus on evacuating two sick persons from a cruise ship hit by a fatal hantavirus outbreak, the World Health Organization said at a briefing on Tuesday.
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