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If she reaches the Senate, Ms. Letlow would replace Senator Bill Cassidy and become the first G.O.P. woman to represent Louisiana in the chamber.
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Supporters of incumbent Republican Sen. Dan Sullivan say a challenger with the same name is not running in "good faith," but a judge says that is not an issue.
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Saturday's election will be the latest test of President Trump's influence in G.O.P. contests.
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